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Mwandishi:

Dkt. Mercy M, CO

Mhariri:

Dkt. Benjamin L, MD

kirusi mumps-ulyclinic

Carbamazepine ni moja kati ya dawa inayotumika kuzuia na kupunguza degedege na pia hutumika katika matibabu ya magonjwa ya kiakili.


Majina ya kibishara


Majina mengine ya kibiashara ya Carbamazepine ni;


  • Tegretol

  • Equetrol

  • Epitol

  • Tegretol XR

  • Carbamazepine chewtabs

  • Carbamazepine CR

  • Carbatrol

  • Teril

  • Carnexiv


Carbamazepine ipo kundi gani la dawa?


Carbamazepine ni dawa iliyo katika makundi yafuatayo;


  • Anticonvulsant

  • Antimanic

  • Dawa za Bipola


Dawa zilizo kundi moja na Carbamazepine


Dawa zilizo kundi moja na Carbamazepine ni ;


  • Brivaracetam

  • Cannabidiol

  • Diazepam

  • Lorazepam

  • Eslicarbazepine

  • Ethosuximide

  • Perampanel

  • Phenytoin

  • Tiagabine

  • Felbamate

  • Fenfluramine

  • Lacosamide

  • Phenobarbital

  • Lamotrigine

  • Levetiracetam

  • Oxcarbazepine

  • Pregabalin

  • Zonisamide


Fomu ya dawa ya Carbamazepine


Dawa hii ipo katika fomu ya;


  • Kidonge

  • Tembe

  • Suspesheni kwaajiri ya kunywa

  • Sindano


Uzito wa dawa ya Carbamazepine


Carbamazepine ina uzito ufuatao;


Vidonge (Epitol)


  • 100mg


Vidonge (Tegretol)


  • 200mg


Vidonge (Tegretol XR)


  • 100mg

  • 200mg

  • 400mg


Tembe (Equetro, Carbatrol)


  • 100mg

  • 200mg

  • 300mg


Suspesheni kwaajiri ya kunywa


  • 100mg/5ml


Sindano


  • 10mg/ml (200mg/20ml Dozi moja kwa vial)


Carbamazepine hutibu nini?


  • Hutumika kutibu ugonjwa wa kifafa

  • Hutumika kutibu Trigeminal neuralgia

  • Hutumika kutibu Bipolar Mania


Namna Carbamazepine inavyoweza kufanya kazi


Carbamazepine inapoingia kwenye kazi hufanya kazi ya kuzuia sodium channel firing na kutibu degedege.


Ufyozwaji wa dawa


Ufyozwaji wa dawa hii hufanyika kwenye mfumo wa chakula mtu akiwa amepata chakula, kiwango cha dawa kinachoonekana kwenye damu ni hadi 85% baada ya mtu kumeza na huchukua masaa 4-5 kwa dawa kuanza kuonekana kwenye damu baada ya mtu kumeza.


Mwingiliano wa Carbamazepine na chakula


Dawa hii ni nzuri ikitumika pamoja na chakula kwani chakula husaidia katika ufyozwaji wa dawa.


Wagonjwa wasiopaswa kutumia Carbamazepine


  • Wagonjwa wenye mzio wa Carbamazepine.

  • Wagonjwa wenye bone marrow suppression.


Utoaji taka wa Carbamazepine mwilini


Asilimia sabini na mbili (72%) ya Dawa hii hutolewa njee kwa njia ya mkojo na asilimia ishirini na nane (28%) hutolewa kwa njia ya haja kubwa.


Matumizi ya Carbamazepine kwa mama mjamzito


Tafiti zinaonesha kuwa dawa hii inaweza kuleta madhara kwa mtoto hivyo tahadhari inatakiwa wakati mama anatumia dawa hii.


Matumizi ya Carbamazepine kwa mama anayenyonyesha


Tafiti zinaonesha kuwa dawa hii inatolewa kwenye maziwa ya mama lakini haijaonesha madhara kwa mtoto hivyo kimoja wapo kinatakiwa kizingatiwe kati ya mama kutumia dawa au mtoto kunyonya.


Dawa zenye muingiliano na Carbamazepine



Dawa zenye mwingiliano mkali na hivyo kutofaa kutumika pamoja na Carbamazepine;

  • Abametapir

  • Abemaciclib

  • Amiodarone

  • Atorvastatin

  • Avapritinib

  • Dexamethasone

  • Diazepam

  • Erythromycin base

  • Esomeprazole

  • Haloperidol

  • Hydrocortisone

  • Isosorbide dinitrate

  • Isosorbide mononitrate

  • Ketoconazole

  • Losartan

  • Methadone

  • Omeprazole

  • Prednisolone

  • Rifampin

  • Warfarin


Dawa zinazoweza kutumika na Carbamazepine chini ya uangalizi;

  • Amitriptyline

  • Amlodipine

  • Artemether/lumefantrine

  • Artesunate

  • Atazanavir

  • Bosentan

  • Carvedilol

  • Clomipramine

  • Cortisone

  • Cyclosporine

  • Dapsone

  • Diazepame

  • Doxycycline

  • Efavirenz

  • Esomeprazole

  • Fluconazole

  • Griseofulvin

  • Haloperidol

  • Heparin

  • Hydrocortisone

  • Ibuprofen

  • Isoniazid

  • Ketamine

  • Lansoprazole

  • Lidocaine

  • Losartan

  • Lumefantrine

  • Metronidazole

  • Mifepristone

  • Omeprazole

  • Phenobarbital

  • Phenytoin

  • Quinine

  • Ritonavir

  • Tamoxifen

  • Testosterone

  • Tinidazole

  • Verapamil

  • Warfarin

  • Zonisamide



Dawa zenye mwingiliano mdogo na Carbamazepine

  • Acetaminophen

  • Ambrisentan

  • Amitriptyline

  • Bupropion

  • Clomipramine

  • Dexmethylphenidate

  • Diclofenac

  • Dosulepin

  • Flurbiprofen

  • Fluvastatin

  • Folic acid

  • Fosphenytoin

  • Frovatriptan

  • Green tea

  • Ibuprofen

  • Ibuprofen iv

  • Imipramine

  • Isotretinoin

  • L-methylfolate

  • Levocarnitine

  • Levothyroxine

  • Liothyronine

  • Lofepramine

  • Maprotiline

  • Mebendazole

  • Meloxicam

  • Niacin

  • Nortriptyline

  • Omeprazole

  • Onabotulinumtoxina

  • Oxcarbazepine

  • Pancuronium

  • Perampanel

  • Phenytoin

  • Piroxicam

  • Protriptyline

  • Sulfamethoxazole

  • Trazodone

  • Trimipramine

  • Vasopressin


Maudhi madogo ya Carbamazepine


  • Ataxia

  • Mwili kuchoka

  • Kusinzia

  • kutapika

  • Kukosa hamu ya kula

  • Kizunguzungu

  • Maumivu ya kichwa

  • Mdomo kukauka

  • Steven Johnson syndrome

  • Kichefuchefu


Ufanye nini endapo utasahau kutumia dozi yako?


Kama umesahau kutumia dozi yako tumia mara pale utakapokumbuka, kama muda wa dozi inayofata umekaribia usimeze dozi uliyosahau endelea na dozi inayofuata kwa muda uliopangiwa na daktari. Usimeze dozi mbili kufidia uliyosahau.

13 Juni 2023, 19:18:46

Dawa Carbamazepine

Imeboreshwa,

30 Oktoba 2021, 18:39:49

Dawa yoyote ni sumu, usitumie dawa pasipo ushauri wa daktari kuepuka madhara kwenye ogani mbalimbali kama figo na ini. Matumizi ya dawa pasipo ushauri wa daktari unaweza kusababisha madhara na usugu wa vimelea vya maradhi kwenye dawa.

​

ULY CLINIC inakushauri siku zote uwasiliane na daktari wako kwa ushauri na tiba kabla ya kuchukua hatua yoyote ile baad aya kusoma makala hii.

Kupata ushauri zaidi na tiba kutoka kwa daktari wa ULY CLINIC bofya Mawasiliano yetu au Pata tiba.

Rejea za mada hii:

  1. Bäck SE, et al. Age dependence of renal function: clearance of iohexol and p-amino hippurate in healthy males. Scand J Clin Lab Invest. 1989 Nov;49(7):641–646.

  2. Bax RP, et al. The pharmacokinetics of meropenem in volunteers. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):311–320.

  3. Burman LA, et al. Pharmacokinetics of meropenem and its metabolite ICI 213,689 in healthy subjects with known renal metabolism of imipenem. J Antimicrob Chemother. 1991 Feb;27(2):219–224.

  4. Christensson BA, et al. Pharmacokinetics of meropenem in subjects with various degrees of renal impairment. Antimicrob Agents Chemother. 1992 Jul;36(7):1532–1537. 

  5. DAVIES DF, SHOCK NW. Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males. J Clin Invest. 1950 May;29(5):496–507.

  6. Douglas JG, et al. The pharmacokinetics of cefuroxime in the elderly. J Antimicrob Chemother. 1980 Jul;6(4):543–549.

  7. Granerus G, et al. Reference values for 51Cr-EDTA clearance as a measure of glomerular filtration rate. Scand J Clin Lab Invest. 1981 Oct;41(6):611–616.

  8. Harrison MP, et al. The disposition and metabolism of meropenem in laboratory animals and man. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):265–277. 

  9. Jones RN, et al. In-vitro studies of meropenem. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):9–29. 

  10. Krutzén E, et al. Plasma clearance of a new contrast agent, iohexol: a method for the assessment of glomerular filtration rate. J Lab Clin Med. 1984 Dec;104(6):955–961.

  11. Ljungberg B, et al. Pharmacokinetics of antimicrobial agents in the elderly. Rev Infect Dis. 1987 Mar-Apr;9(2):250–264.

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