Mwandishi:
Dkt. Mercy M, CO
Mhariri:
Dkt. Benjamin L, MD
Ethosuximide ni moja kati ya dawa inayotumika kuzuia na kupunguza degedege lisiloonekana na la petit mal.
Majina ya kibishara
Majina ya kibashara ya Ethosuximide ni Zarontin
Ethosuximide ipo kundi gani la dawa?
Ethosuximide ni dawa iliyo katika kundi la;
Anticonvulsants
Succinimide
Dawa zilizo kundi moja na Ethosuximide
Dawa zilizo kundi moja na Ethosuximide ni;
Celothin
Methsuximide
Zarontin
Fomu
Dawa hii ipo katika fomu ya;
Tembe
Silapu
Uzito
Ethosuximide ina uzito ufuatao;
Tembe
250mg
Silapu
250mg/5ml
Ethosuximide hutibu nini?
Hutumika kutibu degedege lisiloonekana na lile la petit mal
Namna Ethosuximide inavyoweza kufanya kazi
Ethosuximide inafanya kazi ya kujishikiza kwenye njia za calcium aina T. Njia za calcium aina T hufanya kazi ya kubadirisha kuingia kwa iyoni za calcium kwenye chembe za mishipa ya fahamu na zinahusika kwenye na hivyo kupunguza uzalishaji wa umeme.
Ufyozwaji wa dawa
Ufyozwaji wa dawa hii hufanyika kwenye mfumo wa chakula, kiwango cha dawa kinachoonekana kwenye damu ni hadi 93% baada ya mtu kumeza.
Mwingiliano wa Ethosuximide na chakula
Dawa hii inaweza kutumika mtu akiwa amepata au maziwa.
Wagonjwa wasiopaswa kutumia Ethosuximide
Wagonjwa wenye mzio wa Ethosuximide.
Wagonjwa wenye mzio wa dawa jamii ya succinimide.
Utoaji taka wa Ethosuximide mwilini
Dawa hii hutolewa njee kwa njia ya figo na bile.
Matumizi ya Ethosuximide kwa mama mjamzito
Hakuna tafiti zinazoonesha madhara ya dawa hii kwa mama mjamzito na kwa mtoto aliyeko tumboni hivyo tahadhari inatakiwa wakati mama anatumia dawa hii.
Matumizi ya Ethosuximide kwa mama anayenyonyesha
Tafiti zinaonesha kuwa dawa hii inatolewa kwenye maziwa ya mama lakini haijaonesha madhara kwa mtoto hivyo tahadhari inatakiwa wakati mama anatumia dawa hii.
Dawa zenye muingiliano na Ethosuximide
Dawa zenye mwingiliano mkali na hivyo kutofaa kutumika pamoja na Ethosuximide
Abametapir
Apalutamide
Bremelanotide
Brigatinib
Calcium/magnesium/potassium/sodium oxybates
Conivaptan
Enzalutamide
Fexinidazole
Idelalisib
Ivosidenib
Lumacaftor/ivacaftor
Metoclopramide intranasal
Mifepristone
Mobocertinib
Nefazodone
Pexidartinib
Primidone
Sodium oxybate
Sotorasib
Tucatinib
Voxelotor
Dawa zinazoweza kutumika na Ethosuximide chini ya uangalizi
Amobarbital
Atazanavir
Belzutifan
Berotralstat
Blinatumomab
Bosentan
Brexanolone
Carbamazepine
Cenobamate
Clobazam
Cobicistat
Crizotinib
Crofelemer
Dabrafenib
Darunavir
Deutetrabenazine
Dulaglutide
Duvelisib
Efavirenz
Elagolix
Elvitegravir/cobicistat/emtricitabine/tenofovir df
Encorafenib
Esketamine intranasal
Etravirine
Ferric maltol
Fosamprenavir
Fosphenytoin
Glycerol phenylbutyrate
Iloperidone
Indinavir
Istradefylline
Itraconazole
Ixekizumab
Ketoconazole
Lemborexant
Letermovir
Lopinavir
Lorlatinib
Lurasidone
Midazolam intranasal
Mitotane
Nafcillin
Nelfinavir
Oritavancin
Orlistat
Palbociclib
Phenobarbital
Phenytoin
Rifampin
Rifapentine
Ritonavir
Saquinavir
Tazemetostat
Tecovirimat
Voriconazole
Dawa zenye mwingiliano mdogo Ethosuximide
Acetaminophen
Acetaminophen iv
Acetaminophen a kwenye puru
Amobarbital
Atracurium
Biotin
Butabarbital
Butalbital
Cisatracurium
Cyanocobalamin
Dexmethylphenidate
Dextroamphetamine
Ethotoin
Fosphenytoin
Levocarnitine
Lisdexamfetamine
Methamphetamine
Methylenedioxymethamphetamine
Onabotulinumtoxina
Pancuronium
Pentobarbital
Phenobarbital
Phenytoin
Primidone
Rapacuronium
Rocuronium
Sage
Secobarbital
Succinylcholine
Vecuronium
Maudhi madogo ya Ethosuximide
Mwili kuchoka
Kushindwa kulala vizuri
Homa
Kizunguzungu
Maumivu ya kichwa
Somnolence
Kupoteza hamu ya kula
Kuharisha
Kchefuchefu
Kutapika
Ataxia
Kuchanganyikiwa
Ulimi kuvimba
Degedege
Ufanye nini endapo utasahau kutumia dozi yako?
Kama umesahau kutumia dozi yako tumia mara pale utakapokumbuka, kama muda wa dozi inayofata umekaribia usimeze dozi uliyosahau endelea na dozi inayofuata kwa muda uliopangiwa na daktari. Usimeze dozi mbili kufidia uliyosahau.
13 Juni 2023, 19:18:46
Dawa Ethosuximide
Imeboreshwa,
2 Aprili 2023, 12:07:25
Dawa yoyote ni sumu, usitumie dawa pasipo ushauri wa daktari kuepuka madhara kwenye ogani mbalimbali kama figo na ini. Matumizi ya dawa pasipo ushauri wa daktari unaweza kusababisha madhara na usugu wa vimelea vya maradhi kwenye dawa.
ULY CLINIC inakushauri siku zote uwasiliane na daktari wako kwa ushauri na tiba kabla ya kuchukua hatua yoyote ile baad aya kusoma makala hii.
Kupata ushauri zaidi na tiba kutoka kwa daktari wa ULY CLINIC bofya Mawasiliano yetu au Pata tiba.
Rejea za mada hii:
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Bax RP, et al. The pharmacokinetics of meropenem in volunteers. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):311–320.
Burman LA, et al. Pharmacokinetics of meropenem and its metabolite ICI 213,689 in healthy subjects with known renal metabolism of imipenem. J Antimicrob Chemother. 1991 Feb;27(2):219–224.
Christensson BA, et al. Pharmacokinetics of meropenem in subjects with various degrees of renal impairment. Antimicrob Agents Chemother. 1992 Jul;36(7):1532–1537.
DAVIES DF, SHOCK NW. Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males. J Clin Invest. 1950 May;29(5):496–507.
Douglas JG, et al. The pharmacokinetics of cefuroxime in the elderly. J Antimicrob Chemother. 1980 Jul;6(4):543–549.
Granerus G, et al. Reference values for 51Cr-EDTA clearance as a measure of glomerular filtration rate. Scand J Clin Lab Invest. 1981 Oct;41(6):611–616.
Harrison MP, et al. The disposition and metabolism of meropenem in laboratory animals and man. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):265–277.
Jones RN, et al. In-vitro studies of meropenem. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):9–29.
Krutzén E, et al. Plasma clearance of a new contrast agent, iohexol: a method for the assessment of glomerular filtration rate. J Lab Clin Med. 1984 Dec;104(6):955–961.
Ljungberg B, et al. Pharmacokinetics of antimicrobial agents in the elderly. Rev Infect Dis. 1987 Mar-Apr;9(2):250–264.