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Mwandishi:

Dkt. Mercy M, CO

Mhariri:

Dkt. Benjamin L, MD

kirusi mumps-ulyclinic

Ethosuximide ni moja kati ya dawa inayotumika kuzuia na kupunguza degedege lisiloonekana na la petit mal.


Majina ya kibishara


Majina ya kibashara ya Ethosuximide ni Zarontin


Ethosuximide ipo kundi gani la dawa?


Ethosuximide ni dawa iliyo katika kundi la;


  • Anticonvulsants

  • Succinimide


Dawa zilizo kundi moja na Ethosuximide


Dawa zilizo kundi moja na Ethosuximide ni;


  • Celothin

  • Methsuximide

  • Zarontin


Fomu


Dawa hii ipo katika fomu ya;


  • Tembe

  • Silapu


Uzito


Ethosuximide ina uzito ufuatao;


Tembe


  • 250mg


Silapu


  • 250mg/5ml


Ethosuximide hutibu nini?


Hutumika kutibu degedege lisiloonekana na lile la petit mal


Namna Ethosuximide inavyoweza kufanya kazi


Ethosuximide inafanya kazi ya kujishikiza kwenye njia za calcium aina T. Njia za calcium aina T hufanya kazi ya kubadirisha kuingia kwa iyoni za calcium kwenye chembe za mishipa ya fahamu na zinahusika kwenye na hivyo kupunguza uzalishaji wa umeme.


Ufyozwaji wa dawa


Ufyozwaji wa dawa hii hufanyika kwenye mfumo wa chakula, kiwango cha dawa kinachoonekana kwenye damu ni hadi 93% baada ya mtu kumeza.


Mwingiliano wa Ethosuximide na chakula


Dawa hii inaweza kutumika mtu akiwa amepata au maziwa.


Wagonjwa wasiopaswa kutumia Ethosuximide


  • Wagonjwa wenye mzio wa Ethosuximide.

  • Wagonjwa wenye mzio wa dawa jamii ya succinimide.


Utoaji taka wa Ethosuximide mwilini


Dawa hii hutolewa njee kwa njia ya figo na bile.


Matumizi ya Ethosuximide kwa mama mjamzito


Hakuna tafiti zinazoonesha madhara ya dawa hii kwa mama mjamzito na kwa mtoto aliyeko tumboni hivyo tahadhari inatakiwa wakati mama anatumia dawa hii.


Matumizi ya Ethosuximide kwa mama anayenyonyesha


Tafiti zinaonesha kuwa dawa hii inatolewa kwenye maziwa ya mama lakini haijaonesha madhara kwa mtoto hivyo tahadhari inatakiwa wakati mama anatumia dawa hii.


Dawa zenye muingiliano na Ethosuximide


Dawa zenye mwingiliano mkali na hivyo kutofaa kutumika pamoja na Ethosuximide

  • Abametapir

  • Apalutamide

  • Bremelanotide

  • Brigatinib

  • Calcium/magnesium/potassium/sodium oxybates

  • Conivaptan

  • Enzalutamide

  • Fexinidazole

  • Idelalisib

  • Ivosidenib

  • Lumacaftor/ivacaftor

  • Metoclopramide intranasal

  • Mifepristone

  • Mobocertinib

  • Nefazodone

  • Pexidartinib

  • Primidone

  • Sodium oxybate

  • Sotorasib

  • Tucatinib

  • Voxelotor


Dawa zinazoweza kutumika na Ethosuximide chini ya uangalizi

  • Amobarbital

  • Atazanavir

  • Belzutifan

  • Berotralstat

  • Blinatumomab

  • Bosentan

  • Brexanolone

  • Carbamazepine

  • Cenobamate

  • Clobazam

  • Cobicistat

  • Crizotinib

  • Crofelemer

  • Dabrafenib

  • Darunavir

  • Deutetrabenazine

  • Dulaglutide

  • Duvelisib

  • Efavirenz

  • Elagolix

  • Elvitegravir/cobicistat/emtricitabine/tenofovir df

  • Encorafenib

  • Esketamine intranasal

  • Etravirine

  • Ferric maltol

  • Fosamprenavir

  • Fosphenytoin

  • Glycerol phenylbutyrate

  • Iloperidone

  • Indinavir

  • Istradefylline

  • Itraconazole

  • Ixekizumab

  • Ketoconazole

  • Lemborexant

  • Letermovir

  • Lopinavir

  • Lorlatinib

  • Lurasidone

  • Midazolam intranasal

  • Mitotane

  • Nafcillin

  • Nelfinavir

  • Oritavancin

  • Orlistat

  • Palbociclib

  • Phenobarbital

  • Phenytoin

  • Rifampin

  • Rifapentine

  • Ritonavir

  • Saquinavir

  • Tazemetostat

  • Tecovirimat

  • Voriconazole


Dawa zenye mwingiliano mdogo Ethosuximide

  • Acetaminophen

  • Acetaminophen iv

  • Acetaminophen a kwenye puru

  • Amobarbital

  • Atracurium

  • Biotin

  • Butabarbital

  • Butalbital

  • Cisatracurium

  • Cyanocobalamin

  • Dexmethylphenidate

  • Dextroamphetamine

  • Ethotoin

  • Fosphenytoin

  • Levocarnitine

  • Lisdexamfetamine

  • Methamphetamine

  • Methylenedioxymethamphetamine

  • Onabotulinumtoxina

  • Pancuronium

  • Pentobarbital

  • Phenobarbital

  • Phenytoin

  • Primidone

  • Rapacuronium

  • Rocuronium

  • Sage

  • Secobarbital

  • Succinylcholine

  • Vecuronium


Maudhi madogo ya Ethosuximide


  • Mwili kuchoka

  • Kushindwa kulala vizuri

  • Homa

  • Kizunguzungu

  • Maumivu ya kichwa

  • Somnolence

  • Kupoteza hamu ya kula

  • Kuharisha

  • Kchefuchefu

  • Kutapika

  • Ataxia

  • Kuchanganyikiwa

  • Ulimi kuvimba

  • Degedege


Ufanye nini endapo utasahau kutumia dozi yako?


Kama umesahau kutumia dozi yako tumia mara pale utakapokumbuka, kama muda wa dozi inayofata umekaribia usimeze dozi uliyosahau endelea na dozi inayofuata kwa muda uliopangiwa na daktari. Usimeze dozi mbili kufidia uliyosahau.

13 Juni 2023, 19:18:46

Dawa Ethosuximide

Imeboreshwa,

2 Aprili 2023, 12:07:25

Dawa yoyote ni sumu, usitumie dawa pasipo ushauri wa daktari kuepuka madhara kwenye ogani mbalimbali kama figo na ini. Matumizi ya dawa pasipo ushauri wa daktari unaweza kusababisha madhara na usugu wa vimelea vya maradhi kwenye dawa.

ULY CLINIC inakushauri siku zote uwasiliane na daktari wako kwa ushauri na tiba kabla ya kuchukua hatua yoyote ile baad aya kusoma makala hii.

Kupata ushauri zaidi na tiba kutoka kwa daktari wa ULY CLINIC bofya Mawasiliano yetu au Pata tiba.

Rejea za mada hii:

  1. Bäck SE, et al. Age dependence of renal function: clearance of iohexol and p-amino hippurate in healthy males. Scand J Clin Lab Invest. 1989 Nov;49(7):641–646.

  2. Bax RP, et al. The pharmacokinetics of meropenem in volunteers. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):311–320.

  3. Burman LA, et al. Pharmacokinetics of meropenem and its metabolite ICI 213,689 in healthy subjects with known renal metabolism of imipenem. J Antimicrob Chemother. 1991 Feb;27(2):219–224.

  4. Christensson BA, et al. Pharmacokinetics of meropenem in subjects with various degrees of renal impairment. Antimicrob Agents Chemother. 1992 Jul;36(7):1532–1537. 

  5. DAVIES DF, SHOCK NW. Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males. J Clin Invest. 1950 May;29(5):496–507.

  6. Douglas JG, et al. The pharmacokinetics of cefuroxime in the elderly. J Antimicrob Chemother. 1980 Jul;6(4):543–549.

  7. Granerus G, et al. Reference values for 51Cr-EDTA clearance as a measure of glomerular filtration rate. Scand J Clin Lab Invest. 1981 Oct;41(6):611–616.

  8. Harrison MP, et al. The disposition and metabolism of meropenem in laboratory animals and man. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):265–277. 

  9. Jones RN, et al. In-vitro studies of meropenem. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):9–29. 

  10. Krutzén E, et al. Plasma clearance of a new contrast agent, iohexol: a method for the assessment of glomerular filtration rate. J Lab Clin Med. 1984 Dec;104(6):955–961.

  11. Ljungberg B, et al. Pharmacokinetics of antimicrobial agents in the elderly. Rev Infect Dis. 1987 Mar-Apr;9(2):250–264.

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