Ewing’s tumor
Introduction
Ewing’s tumor is a very rare type of cancerous tumor that grows in bones or the soft tissue around bones including cartilage and nerves.
Pathophysiology
Signs and symptoms
• A lump near skin that feels warm and soft to the touch
• Constant low grade fever
• Bone pain worsening during exercise or during the night
• Broken bones without an obvious cause
• Weight loss
• Weakness
• Paralysis of jaw
Diagnostic criteria
• Painful swelling accompanied with fever
• It is characterized by extraordinarily fast growth
• Radiographically: Poorly defined solitary osteolytic lesion, irregular moth– eaten appearance which may be undetectable in serial images for a long period. Histological diagnosis is needed
Investigation
• X-rays
• Bone scan with radioactive dye
• Magnetic resonance imaging (MRI)
• Computed tomography scan (CAT/CT scan)
• PET scan
• CBC for RBC, WBC and hemoglobin
• Biopsy- to confirm for Ewing’s sarcoma
• Bone marrow aspiration and biopsy
Treatment
Non-pharmacological
- The initial treatment is wide excision, if not possible radiation should be considered.
Pharmacological
- Combination chemotherapy should be given
Prevention
-
Updated on,
4 Novemba 2020, 10:40:54
References
1. STG
2. Web Md. Ewing sarcoma. https://www.webmd.com/cancer/ewings-sarcoma#. Accessed on 4.11.2020
3. Web MD. https://www.webmd.com/cancer/ewings-sarcoma#1. Accessed on 4.11.2020